WebJan 3, 2024 · In this study, we found that thioredoxin-interacting protein (Txnip), a regulator of oxidoreductase, controlled reactive oxygen species (ROS) metabolism via the nuclear … WebMay 1, 2014 · Thioredoxin-interacting protein (TXNIP) has emerged as a key regulator of important cellular processes including redox state (1– 5) and apoptosis (6– 10), is involved in inflammasome activation (), inflammation, and endoplasmic reticulum stress (12, 13), and plays a particularly critical role in pancreatic β-cell biology (6– 9).Initially identified as the …
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WebApr 1, 2008 · In the current issue of Diabetes, Chen et al. ( 4) provide evidence that the loss of β-cell mass in response to elevated concentrations of glucose is the results of enhanced expression of a single protein, thioredoxin-interacting protein (TXNIP). TXNIP participates in control of the redox state of a cell by interacting and inhibiting ... Web文档翻译; 收录引证; 论文查重 ... A thioredoxin domain-containing protein 12 from black rockfish Sebastes schlegelii: Responses to immune challenges and protection from apoptosis against oxidative stress. ... Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals. how do you spell shredding
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WebThioredoxin-interacting protein (TXNIP) has emerged as a key pathological regulator of diseases, particularly those associated with glucose and lipid abnormalities and … WebMar 13, 2024 · Upon accumulation of data via a wide array of literature surveys, it has been found that Thioredoxin Interacting Protein (TXNIP) presents itself as a vital factor in controlling the production and loss of beta islet cells. TXNIP inhibits the action of the Thioredoxin (TRX) protein found in the beta cells thereby rendering it ineffective in ... Web2. TXNIP. Thioredoxin-interacting protein (TXNIP), also known as vitamin D upregulated protein-1 (VDUP-1) or thioredoxin-binding protein-2 (TBP-2), is a multifunctional protein that is essential for many cellular processes such as metabolic activities, growth, division, and cell death [].It was initially believed that TXNIP was restricted only to the cytoplasm. phoneears