Web24 Aug 2024 · Germinal centers (GC) allow diversification and maturation of the antibody response towards the foreign antigen. While self-tolerance mechanisms controlling self-reactivity during B cell... Web11 Apr 2024 · Thus, eliciting the RBD-specific B cells to the longitudinal germinal center reaction confers potent immunity to broad SARS-CoV-2 variants emerging one after …
Dynamics of B cells in germinal centres - Nature
Web23 Apr 2024 · The germinal center reaction involves multiple immune cells and is tightly controlled by lineage-specific transcription factors. In this chapter, I will discuss the … Web1 Nov 2010 · The germinal center (GC) reaction is the basis of T-dependent humoral immunity against foreign pathogens and the ultimate expression of the adaptive immune … hyundai near new orleans
Teresa Fuertes Novella, PhD - Scientist 匿 Cell biology B cell ...
Web9 Dec 2010 · EZH2 is up-regulated in normal germinal center (GC) B cells and is implicated in lymphomagenesis. To explore the transcriptional programs controlled by EZH2, we performed chromatin immunoprecipitation (ChIP-on-chip) in GC cells and found that it binds approximately 1800 promoters, often associated with DNA sequences similar to Droso … WebHowever, not all immune cell subsets that express PD-1 also target tumor cells. Utilizing the immune response of the germinal center reaction to seasonal influenza vaccination as a readout, Herati et al. introduced vaccination as an analytical tool to predict adverse effects beyond anticancer responses . WebDuring the GC reaction, rare B cell subsets express surface markers that identify pre-memory cells as well as transcription factors that promote the generation of pre-PCs such as Irf4 … hyundai near newtown pa