Webb26 nov. 2024 · In addition, using loss-of-function and mutants of sox2 and sox3, we find that the combined activity of both genes is essential for lateral line development and regeneration. The capability of sox2/sox3 expressing stem cells to produce new hair cells, hair cell-precursors, and supporting cells after damage was analyzed in detail by time …
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Webb23 mars 2024 · SOX3 promotes migration, invasiveness, and EMT in OS cells via transcriptional activation of Snail1 expression, suggesting that SOX3 is a novel regulator … Webb1 juli 2024 · Generation of Sox3 Sox2KI and Sox3 KO mice with CRISPR mutagenesis. (A) Schematic showing the strategy for generation of the Sox3 Sox2KI mice. (B, C) PCR screening of founder mice. (D) Sox2 transcript levels were measured in 11.5 dpc brains by qPCR with primers located in the Sox2 ORF. (E) qPCR showing expression from the … theft of mail fss
SOX3 protein expression summary - The Human Protein Atlas
Webb26 dec. 2024 · Folliculogenesis is essential for production of female gametes in vertebrates. However, the molecular mechanisms underlying follicle development, particularly apoptosis regulation in ovary, remain elusive. Here, we generated sox3 knockout zebrafish lines using CRISPR/Cas9. sox3 knockout led to follicle development … Webb3 feb. 2024 · SOX3 gene, which belongs to SOX family Sry-related High Mobility Group Box, located at Xq27.1. It is a 1,341 nucleotides single exon gene. It is highly expressed throughout development in the pituitary and central nervous system (CNS), and is recognized to have a key role in regulating embryogenesis and CNS development [ 1 ]. Webb24 jan. 2024 · Sox3 null mice exhibit a ventral extension of the anterior pituitary that penetrates, and generates a mass beneath, the sphenoid bone These data define Dbx1 … thea hotel chalkidiki