Webb25 feb. 2015 · The second-generation versions of PLINK will offer dramatic improvements in performance and compatibility. For the first time, users without access to high-end computing resources can perform several essential analyses of the feature-rich and very large genetic datasets coming into use. Webb29 mars 2024 · Share your in-game results in a community where it’ll be appreciated by thousands of gamers. - Plink supports all popular games, including Call of Duty, Apex Legends, Battlefield 5, Destiny 2, Overwatch, …
PLINK: Whole genome data analysis toolset - Harvard University
Webb16 feb. 2024 · plink的语境叫“case and control”,即表型值数据是两类数据:1,2,其中0和-9都表示缺失。 可以选择的方法有卡方检验和逻辑斯蒂回归(X2关联分析和logistic分析)。 –assoc ,不允许有协变量 –logistic ,允许有协变量,如果考虑协变量,速度变慢。 比 assoc 速度慢。 2.2 连续性状(定量性状) 这里的性状时连续性状,也就是除了1,2,0, … Webb28 sep. 2024 · 作为关联分析最常用的工具,plink支持多种关联分析的算法。 对于经典的case/control关联分析,该软件支持allele和genotype两个层次的关联分析,具体做法如下 1. allele association test 对于每个snp位点. 统计case/control两组中minor和major allele的频数,得到如下所示的表格 对于上述的2 X 2数据,使用卡方和费舍尔精确检验来进行关联分 … inclination\u0027s 5s
利用PLINK进行GWAS分析(五)
Webb16 jan. 2024 · PLINK's primary job is management and analysis of position-based SNP-like data for thousands of samples, and it is optimized for this setting. Here are a few things … WebbHowever, certain PLINK files can be large: e.g. .genome files for large samples, dosage output for whole-genome imputation of all HapMap SNPs, etc. Therefore, a large hard drive is desirable: not including storage for CEL files, a drive of at least 200Gb would be good. PLINK does not specifically take advantage of multi-core processors. Webb29 nov. 2024 · plink格式文件的介绍及相互转换 1. map/ped 文件 2. bim/fam/bed文件 3. plink格式文件的相互转换 4. 利用plink进行数据预处理(修剪SNP集) 5. 总结 Plink常用的文件格式有两套:map/ped 和 bim/fam/bed。 两组文件均没有列名,且每一列表示的意思是一定的。 几种格式之间可以相互转换。 推荐使用BED/BIM/FAM这种格式,读取速度快。 … inclination\u0027s 5t