WebApr 11, 2024 · By performing mass spectrometry and proteomics analyses, we further demonstrated that IDH2-deficiency in hepatocytes accelerated ATP production by increasing forward TCA cycle flux, thus promoting glycolysis pathway and decreasing glycogen synthesis at refeeding state, and inhibiting hepatic gluconeogenesis, increasing β … WebApr 11, 2024 · Given that hepatic gluconeogenesis and glycogenolysis are concomitantly involved in maintaining euglycemia during starvation, the following studies focus on these two aspects. In vivo, after pyruvate injection, IDH2 LKO mice exhibited lower blood glucose levels, both at SD and HFD feeding ( Fig. 2 A-B ).
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Web26K views 2 years ago Digestive System & Metabolism In this video, Dr Mike explains what happens metabolically in the fed state (immediately after eating a meal). This 'absorptive-state' is... Web2 main roles of cortisol in fasted state. 1) initiate protein catabolism for gluconeogensis. … grill grate with handle
Hepatic IDH2 regulates glycolysis and gluconeogenesis
WebGlycolysis is the metabolic process by which glucose is broken down, while … WebGlycolysis is dominant in the fed state in which glucose is abundant. Glycolytic … WebInsulin is released in a well fed state. From a sugar standpoint, it means you've got a lot of sugar floating around your body. Having too much blood sugar is bad, so insulin makes your cells take up glucose to maintain normal blood sugar levels. Extra pyruvate from glycolysis can be converted into fatty acids for energy storage. grill greats ceramic grill tiles